FLuc circular RNA

FLuc circular RNA is capable of expressing luciferase protein in cells after transfection. The protein was originally extracted from the firefly (Photinus pyralis). Luciferase can catalyze the oxidation of luciferin to produce oxyluciferin, emitting yellow-green bioluminescence (wavelength of 550-570 nm), and the light intensity directly reflects the expression level of luciferase. This product can serve as a positive control for mRNA transfection, and further be used for screening and validation of delivery formulations or expression systems.

This circular RNA features following structure: 

• IRES region for translation initiation
• Poly(A) tail
• 5’ and 3’ UTR with proven efficient translation 
• ORF with codon optimization

Competitive advantage of AmRNA product:

At AmRNA, we are committed to delivering ready-to-use mRNA of the highest quality standards (only A grade). Each mRNA is produced using state-of-the-art industrial synthesis and purification technologies, ensuring ultra-high purity, capping efficiency, and poly(A) tail integrity. Residual impurities such as protein, DNA, and dsRNA are reduced to trace levels to minimize potential immunogenicity. Our comprehensive quality control panel rigorously verifies every critical attribute to ensure batch-to-batch consistency, ensuring data reproducibility in both in vitro and in vivo applications.