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AA-MRNA005

hEPO mRNA

hEPO mRNA

Human Erythropoietin mRNA (N1-Me-Pseudo UTP).

Size
Regular price $299.00 USD
Regular price Sale price $299.00 USD
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Quantity

Length

847 nt

Concentration

1 mg/mL

Buffer

MilliQ water or 1mM sodium citrate pH 6.5

Storage Conditions

-20°C for short term (<3 months) storage and -80°C for long term storage.

Documents

Pardon the dust, work in progress.

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Product description

hEPO mRNA (N1-Me-Pseudo UTP) encodes human erythropoietin (hEPO), a hormone that controls red blood cell production or erythropoiesis. hEPO also plays a role in wound healing and the response of the brain to nerve injury. In addition to significantly promoting
hematopoiesis, hEPO also has effects on angiogenesis, brain protection, kidney protection, heart protection, immune regulation, and the protection of the digestive and reproductive systems. This product is an in vitro transcribed hEPO mRNA that can be transfected into cells and enables efficient expression. It can be used for experimental studies and validation of the regulatory functions of hEPO in various biological processes.

This mRNA features following structure: 

  • Cap 1 (N7-methylguanosine Cap) with high capping efficiency 
  • Poly(A) tail with 100 consecutive A 
  • 5’ and 3’ UTR with proven efficient translation 
  • ORF with codon optimization
  • N1-methyl-pseudouridine modification

Competitive advantage of AmRNA product:

At AmRNA, we are committed to delivering ready-to-use mRNA of the highest quality standards (only A grade). Each mRNA is produced using state-of-the-art industrial synthesis and purification technologies, ensuring ultra-high purity, capping efficiency, and poly(A) tail integrity. Residual impurities such as protein, DNA, and dsRNA are reduced to trace levels to minimize potential immunogenicity. Our comprehensive quality control panel rigorously verifies every critical attribute to ensure batch-to-batch consistency, ensuring data reproducibility in both in vitro and in vivo applications.

Quality Control Specifications


Quality Attributes QC Method Release Standard
Appearance Visual inspection Clear and free of foreign particles
pH pH meter Target +/- 0.2 
Content UV-Vis Target +/- 5%
A260/280 UV-Vis 1.8-2.2
Identity Sequencing Sequence fully match
Integrity/Purity

Capillary electrophoresis 

>90.0%
Capping Efficiency LC-MS >95.0%
Tailed% HPLC >95.0%
dsRNA ELISA <0.1%
Endotoxin

LAL assay 

<10 EU/mg

Applications

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